Evidence You Can Trust
Drug Discovery, Efficacy Assessment, and Disease Modeling
We solve complex scientific problems through customized experimental approaches.
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Delivering robust, reproducible scientific evidence to advance your project.
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Designing biologically relevant methodologies around your specific objectives.
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Answering your scientific question through tailored experimental workflows.
Tailored for Preclinical Research, Safety Evaluation, and Mechanism-of-Action Studies
We develop customized New Approach Methodologies (NAMs) to address the scientific objectives of each project.
Our methodologies combine established experimental systems, validated technologies, and analytical methods with advanced cell models, novel assays, and specialized research tools.
Scalable Platform Technologies
Designed for Compound Screening, Efficacy Comparison, and Donor-Specificity Assessment
Reliable methodologies require robust experimental platforms.
Our barrier tissue, tumor, hepatic, and endothelial platforms are engineered for reproducibility and scalability in standard 96- and 384-well formats.
Our platform technologies support customized NAMs across diverse biological applications.
Assessing Endothelial and Microvascular Liabilities
We developed advanced human endothelial cell and microvascular models to analyze angiogenesis, capillary network formation, and barrier function.
These models are applied to compound screening, mechanism-of-action studies, safety assessment, and disease modeling.
Research Services
Discovery & Preclinical Research
Assay Development | Customized assay design, optimization, and validation
Drug Discovery & Screening | Compound screening, mechanism-of-action studies, and lead optimization
Drug Safety & Toxicology | Cytotoxicity, hepatotoxicity, vascular safety, and barrier function assessment
Disease Modeling | Human-relevant disease models for target validation, efficacy studies, and translational research
Advanced Cell Models (ACM)
Microvascular & Vascular Biology | Human microvascular networks for endothelial biology, angiogenesis, vascular safety, and microcirculation research
Barrier Tissues | 96-well skin, airway, and intestinal barrier models for barrier function, permeability, inflammation, and safety assessment
Immuno-Oncology | 3D tumoroid models for tumor microenvironment, immune-cell interactions, and efficacy studies
Drug Metabolism | Human hepatic spheroid models for drug metabolism, hepatotoxicity, and repeated-dose studies
Molecular Biology & Analytical Services
Biologics & Molecular Biology | Protein expression and purification, antibody-drug conjugates (ADCs), antibody-RNA conjugates, and virus-mediated gene delivery
Analytical Services | High-content imaging and analysis, particle characterization, and formulation stability testing
Trusted by the Scientific Community
Working With Us
We recognize that every scientific question is unique. Rather than adapting your project to a predefined assay, we develop customized experimental methodologies designed around your scientific objectives.
Testimonials
"Creative Scientist has been an exceptional partner for our molecular and cell biology projects: highly flexible, detail-oriented, and consistently reliable. Their team adapts quickly to our evolving needs while maintaining scientific rigor. We value our long-standing relationship and trust their expertise."
Julian Andreev, Ph.D.
Senior Fellow
Regeneron Pharmaceuticals
"Creative Scientist impressed us with the speed and precision of their custom assay development. They went above and beyond to meet tight deadlines and deliver high-quality data. Their commitment to getting results made a real difference for our project."
Sara Lenzen, Ph.D.
Senior Scientist
AgBiome
"We needed results fast, and Creative Scientist delivered. Their cell-based assay was the right fit for our application and worked right out of the gate. Their consultative approach to experimental design, grounded in deep expertise in cell systems and biology, helped keep our project on track. It truly felt like they were invested in our success.”
Sandy Merkel-DeJames, Ph.D.
Founder & CEO
Acclivity Technologies