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Testing Microvascular Toxicity in 3D

Vascular Microcapillaries

Microvascular Networks in 384-Well Plates

High-Throughput. Human-Relevant.

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Use our service to quantify the impact of active ingredients, drugs, or toxic chemicals on microcirculation. Use our microvascular network formation assay to study mechanisms of wound healing or tumorigenesis.

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We differentiate human donor-specific Endothelial Progenitor Cells (EPCs) and Human Umbilical Vein Endothelial Cells (HUVECs) into robust microvascular networks in 384-well plates.

Testing Anticancer Drugs in 3D

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Tumoroids in 96-well plates

3D Tumor Models (Tumoroids) in 96-Well Plates

Reproducible. Structured. Ready for Screening.

 

Use our service to prioritize anticancer drugs targeting:

  • Tumor cells

  • Tumor-associated fibroblasts

  • Tumor microvasculature

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We grow highly reproducible tumor-like organoids (tumoroids) in 96-well plates, incorporating fibroblasts and endothelial cells to recreate essential features of the tumor microenvironment.

Testing Drug Permeability in 3D

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airway epithelial Barrier

96-Well Barrier Tissue Platform

Reliable. Scalable. Customizable.

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Use our scalable and cost-effective high-throughput platform to:

  • Study barrier tissue dysfunction

  • Quantify drug permeability

  • Assess barrier disruption by drugs and toxic chemicals

 

We grow barrier tissues in 96-well format compatible with:

  • Off-the-shelf cell lines (e.g., MDCK, Caco-2)

  • Customer-supplied (e.g., gastrointestinal, skin, or airway epithelial) cells

Contact us to learn more

Testing Drug Metabolism in 3D

Hepatic spheroid

Testing Metabolism in 96- and 384-Well Plates

Reduce Animal Use. Maximize Predictive Power.

 

Use our service to reduce the cost of studying metabolism and hepatic toxicity of drugs, cosmetic ingredients, and environmental toxins.

 

We provide both 2D and 3D cell models as physiologically relevant alternatives for the analysis of the metabolism of your active ingredients in vitro, supporting R&D in:

  • Cancer,

  • Liver diseases (steatosis, fibrosis),

  • Environmental exposure studies.

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